Prionex® - Protein stabilizer by Pentapharm

Due to the chemical nature and the standardised quality, Prionex® can be used as an inert protein stabilizer and as an additive for cell culture media.

Prionex® Application

Prionex® is a 10% aqueous solution of a polypeptide fraction of highly purified dermal collagen of porcine origin which has excellent protein stabilizing properties. Prionex® is prepared by partial hydrolysis and is terminally sterilized. It is free from cartilage, bone and plasma components and is therefore a pure form of partially hydrolyzed gelatine type A.

Prionex® is a porcine collagen peptide fraction that has multiple advantages

  • Optimizes stability of biological activity
  • Improves conditions for lyophilisation and heat treatment
  • Avoids denaturation by chaotropic agents or solvents
  • Extends shelf life for enzymes and proteins
  • High consistency stabilizer
  • Non-toxic and non-antigenic
  • Free from nucleic acids, polysaccharides and lipids
  • Free from any additives

MW

The average molecular weight is approx. 20’000 Da, estimated by gel permeation chromatography.

Solubility

Prionex® is freely soluble in water, diluted electrolyte solutions, glycerol and DMSO as well as in diluted ethanol and ammonium sulphate solutions below 20% saturation. Storage: 15 - 25°C, protected from light

References

Gaffney PJ, Edgell TA, Dawson PA, Ford AW, Stocker K. A pig collagen peptide fraction. A unique material for maintaining biological activity during lyophilization and during storage in the liquid state. J Pharm Pharmacol 1996; 48: 896-8.

Prionex® Data Sheet

 

Prionex® Price and Conditions

Prionex® is a Pentapharm product. Please contact us for best conditions.

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