Pefabloc® FG binds with a high affinity to fibrinogen, inhibits fibrin polymerization, modifies the mechanical properties of fibrin clots and can dissociate non-stabilized fibrin gels.

Application

Pefabloc® FG is added to fibrinogen containing reaction mixtures to inhibit disturbing fibrin-related turbidity, gel formation and fibrin deposition in diagnostic and preparative procedures (e. g. measurement of thrombin generation in plasma). Pefabloc® FG is also used to inhibit fibrin formation during purification and processing of clotting factors and other plasma proteins.

Pefabloc® TH can be used in diagnostic systems, analytical applications, research and industrial purification processes to exclude undesired thrombin activity. It can also be used as a potent anticoagulant in in-vitro test systems.