Chromogenic Substrates

Pefachrome®

Specific synthetic chromogenic peptide substrates for the measurement of the activity of various serine proteases in the field of:
  • Coagulation
  • Fibrinolysis
  • Kallikrein-kinin system
  • Complement system

The chromogenic peptides are also used in quality control of pharmaceutical and other preparations.

Packing sizes: 25 mg, 1 g, 5 g (further packaging on request)

The Substrate Toolbox for Coagulation Enzymes

Substrate for Thrombin
Ref Name Description Downloads
081-01 Pefachrome® TH 5244 Tos-Gly-Pro-Arg-pNA · AcOH
081-05 Pefachrome® TH 5247 H-D-CHG-But-Arg-pNA · 2AcOH
081-09 Pefachrome® TH 5251 H-D-CHA-Ala-Arg-pNA · 2AcOH
081-11 Pefachrome® FXIIa/TH 5253 H-D-CHA-Gly-Arg-pNA · 2AcOH
081-15 Pefachrome® TH 5256 CH3OCO-Gly-Pro-Arg-pNA · AcOH
081-66 Pefachrome® TH 8198
(corresp. S-2238)		 H-D-Phe-Pip-Arg-pNA · 2HCl
801206 Pefachrome® TH 1206 H-Sar-Pro-Arg-pNA · 2HCl
Substrate for the determination of Thrombin generation
Ref Name Description Downloads
081-17 Pefachrome® TG H-ß-Ala-Gly-Arg-pNA · 2AcOH
Substrate for Factor Xa
Ref Name Description Downloads
085-01 Pefachrome® FXa5277 CH3SO2-D-Leu-Gly-Arg-pNA · AcOH
085-03 Pefachrome® FXa5279 CH3OCO-D-CHG-Gly-Arg-pNA · AcOH
085-06 Pefachrome® FXa/LAL 5288 CH3OCO-D-CHA-Gly-Arg-pNA · AcOH
085-27 Pefachrome® FXa8595
(corresp. S-2765)		 Cbo-D-Arg-Gly-Arg-pNA · 2HCl
802893 Pefachrome® FXa 2732
(corresp. S-2732)		 Suc-Ile-Glu (gamma-Pip)-Gly-Arg-pNA · HCl
Substrate for Factor VIIa
Ref Name Description Downloads
093-01 Pefachrome® FVIIa CH3SO2-D-CHA-Abu-Arg-pNA · AcOH
Substrate for Factor Xlla
Ref Name Description Downloads
081-11 Pefachrome® FXIIa/TH 5253 H-D-CHA-Gly-Arg-pNA · 2AcOH
Substrate for Urokinase
Ref Name Description Downloads
082-33 Pefachrome® uPA8294
(corresp. S-2444)		 pyro-Glu-Gly-Arg-pNA · 2HCl
Substrate for tPA
Ref Name Description Downloads
091-01 Pefachrome® tPA CH3SO2-D-CHA-Gly-Arg-pNA · AcOH
091-03 Pefachrome® tPA5312 CH3SO2-D-Phe-Gly-Arg-pNA · AcOH
Substrate for Plasmin
Ref Name Description Downloads
083-01 Pefachrome® PL/Tryp 5261 Tos-Gly-Pro-Lys-pNA · AcOH
083-02 Pefachrome® PL5262 H-D-But-CHA-Lys-pNA · 2AcOH
083-03 Pefachrome® PL5263 H-D-Nva-CHA-Lys-pNA · 2AcOH
083-04 Pefachrome® PL5264 H-D-Nle-CHA-Lys-pNA · 2AcOH
Substrate for activated Protein C
Ref Name Description Downloads
089-02 Pefachrome® PCa H-D-Lys(Cbo)-Pro-Arg-pNA · 2AcOH
089-07 Pefachrome® PCa 5297 Pad-Pro-Arg-pNA·AcOH
Substrate for C1-esterase
Ref Name Description Downloads
087-03 Pefachrome® C1E 5603 CH3CO-Lys(Cbo)-Gly-Arg-pNA · AcOH
Substrate for Trypsin
Ref Name Description Downloads
084-01 Pefachrome® TRY5274 Cbo-Val-Gly-Arg-pNA · AcOH
083-01 Pefachrome® PL/Tryp 5261 Tos-Gly-Pro-Lys-pNA · AcOH
Substrate for the determination of bacteria endotoxins
Ref Name Description Downloads
086-11 Pefachrome® LAL 5288 CH3OCO-D-CHA-Gly-Arg-pNA · AcOH
Substrate for Factor IXa
Ref Name Description Downloads
095-20 Pefachrome® FIXa CH3SO2-D-CHG-Gly-Arg-pNA · AcOH

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